Search on: RETROGRADE DEGENERATION 
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Descriptor English:   Retrograde Degeneration 
Descriptor Spanish:   Degeneración Retrógrada 
Descriptor Portuguese:   Degeneração Retrógrada 
Synonyms English:   Axon Reaction
Nissl Degeneration
Retrograde Degeneration, Transneuronal  
Tree Number:   C23.550.737.500
Definition English:   Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons. 
History Note English:   91(75); was see under NERVE DEGENERATION 1975-90; NISSL DEGENERATION was see NERVE DEGENERATION 1997, was heading 1975-96 (see under NERVE DEGENERATION 1975-90) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   12599 
Unique Identifier:   D012183 

Occurrence in VHL:
 

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